Friday, March 29, 2013

Court approves American Airlines-US Airways merger

A judge on Wednesday approved AMR Corp's plan to merge with US Airways Group , a step toward creating the world's largest airline.

AMR, parent of American Airlines and in bankruptcy since November 2011, must still construct a formal restructuring plan incorporating the merger that meets court and creditor approval before the airline can emerge from bankruptcy.

American Airlines announced the plan to combine with US Airways last month, a deal that also requires regulatory approval.

In a crowded Manhattan courtroom on Wednesday, U.S. Bankruptcy Judge Sean Lane declined to approve, for now, a planned $19.9 million severance package for Tom Horton, AMR's outgoing chief executive.

Lane said he was uncertain as to whether the severance package requires his approval at all, or whether the matter is more appropriate for inclusion in AMR's formal restructuring plan.

That plan, which all debtors in bankruptcy must propose, will lay out how creditors will get paid back, and will require creditor approval.

The fate of the severance payment is unclear. The version of the merger agreement that earned the judge's approval may have to be amended to remove it.

Jack Butler, a lawyer for AMR's creditors' committee, said it was too early to tell how the parties will deal with the severance issue.

"The companies said they were prepared to amend the merger agreement in any respect, and I expect that there will be an amendment," Butler said after the hearing.

AMR filed for bankruptcy citing untenable labor costs after years of futile attempts to negotiate cost savings from its unionized workforce. It had been the last major U.S. carrier to go through bankruptcy, after its competitors underwent the same process in the last decade.

Wednesday's approval was a key moment in AMR's 16-month odyssey through reorganization under Chapter 11 of the bankruptcy code. Stephen Karotkin, a lawyer for AMR, called Wednesday's hearing a "watershed event" that moves AMR a step closer to exiting bankruptcy.

The airline began its bankruptcy process flatly opposed to merging while still in bankruptcy, but eventually relented to pressure from its creditors' committee, represented by Butler and Jay Goffman, both lawyers at Skadden Arps Slate Meagher & Flom.

US Airways Chief Executive Doug Parker wooed AMR aggressively, taking advantage of AMR's labor relations problems to appeal to its unions.

US Airways hammered out a tentative deal with the unions last April, before formal merger talks between the two companies' management teams had gone into full swing.

The creditors' committee eventually convinced AMR to adopt a protocol to evaluate a merger, and played a large role in analyzing the net savings and benefits from a merger.

AMR's current shareholders are expected to receive a 3.5 percent equity stake in the new firm, which would make it one of the few major bankruptcies in which equity holders earn some recovery.

The Skadden legal team advising the creditors' committee also played a central part in negotiating the new management structure, including the details of Horton's severance package.

Parker will serve as CEO of the combined carrier, while Horton, who became AMR's CEO when it filed for bankruptcy, will serve as chairman of the airline through the first annual meeting of shareholders. After that Parker will take on the chairman role.

The merger is expected to close in the third quarter.

The case is In re AMR Corp et al, U.S. Bankruptcy Court, Southern District of New York, No. 11-15463.

Copyright 2013 Thomson Reuters.

Source: http://feeds.nbcnews.com/c/35002/f/653351/s/2a115a25/l/0L0Snbcnews0N0Cbusiness0Ccourt0Eapproves0Eamerican0Eairlines0Eus0Eairways0Emerger0E2B9117378/story01.htm

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Thursday, March 28, 2013

Prebiotics: Do supplements in baby formula help prevent allergies?

Mar. 25, 2013 ? Prebiotic supplements in infant formula may help to prevent eczema, according to a systematic review published in The Cochrane Library. However, the review highlights a lack of high quality evidence for the effects of prebiotics in preventing allergies.

It is thought that bacteria lining the gut may play an important role in a child developing sensitivities to certain foods and allergens, regulating immune responses and determining how they will react to the same substances in later life. Prebiotics are indigestible components of breast milk, fruit and vegetables that stimulate the growth and activity of healthy bacteria in the gut. They are distinct from probiotics, which are cultures of live bacteria such as those added to yoghurts and infant formula. Prebiotics can also be added to infant formula. However, it is unclear exactly what effect these supplements have on the development of allergies.

The researchers drew together data from four studies involving a total of 1,428 children. Children were given formula containing prebiotic supplements or, as a control, standard formula. Studies followed children to between four months and two years of age and reported the number who developed allergies. Eczema was significantly reduced in children who were fed formula containing prebiotics. Only two studies investigated asthma. The number of children who developed asthma was similar whether they were given formula with added prebiotics or without. In one study looking at urticaria (hives), giving children formula containing prebiotics did not prevent any cases of the allergy.

Only one study assessed the effect of giving formula containing prebiotics to high-risk children, who had close family members with allergies. In this study, prebiotics reduced both eczema and asthma, but there were no significant reductions in allergies overall in high-risk children. "Given these findings, it remains unclear whether the use of prebiotics should be restricted to infants at high risk of allergy or may have an effect in low risk populations," said lead researcher, John Sinn of the University of Sydney in Sydney, Australia.

"Overall, we found some evidence that infant formula containing prebiotic supplements can help prevent eczema in children up to two years of age," said Sinn. "However, the quality of existing evidence is generally low or very low. More high quality research is needed before we can recommend routine use of prebiotics for prevention of allergy."

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The above story is reprinted from materials provided by Wiley.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. JK Sinn, DA Osborn. Prebiotics in infants for prevention of allergy and food hypersensitivity. The Cochrane Library, 2013 (in press) DOI: 10.1002/14651858.CD006474

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/szTO79OWy3I/130328075716.htm

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Google adds Street View to ghost town inside Japan nuclear zone

AP / Google

This March 2013 image released by Google shows its camera-equipped Street View vehicle as it moves through Namie in Japan, a nuclear no-go zone where former residents have been unable to live since they fled from radioactive contamination from the Fukushima Dai-ichi nuclear power plant two years ago.

By Yuri Kageyama, Associated Press

TOKYO? ? Concrete rubble litters streets lined with shuttered shops and dark windows. A collapsed roof juts from the ground. A ship sits stranded on a stretch of dirt flattened when the tsunami roared across the coastline. There isn't a person in sight.

Google Street View is giving the world a rare glimpse into one of Japan's eerie ghost towns, created when the March 2011 earthquake and tsunami sparked a nuclear disaster that has left the area uninhabitable.

The technology pieces together digital images captured by Google's fleet of camera-equipped vehicles and allows viewers to take virtual tours of locations around the world, including faraway spots like the South Pole and fantastic landscapes like the Grand Canyon.

AP / Google

This screenshot, made from the Google Maps site provided March 27, 2013 by Google, shows stranded ships left as a testament to the power of the tsunami which hit the area two years ago.

Now it is taking people inside Japan's nuclear no-go zone, to the city of Namie, whose 21,000 residents have been unable to return to live since they fled the radiation spewing from the Fukushima Dai-ichi nuclear power plant two years ago.

Koto Naganuma, 32, who lost her home in the tsunami, said some people find it too painful to see the places that were so familiar yet are now so out of reach.

She has only gone back once, a year ago, and for a few minutes.

"I'm looking forward to it. I'm excited I can take a look at those places that are so dear to me," said Naganuma. "It would be hard, too. No one is going to be there."

Namie Mayor Tamotsu Baba said memories came flooding back as he looked at the images shot by Google earlier this month.

He spotted an area where an autumn festival used to be held and another of an elementary school that was once packed with schoolchildren.

"Those of us in the older generation feel that we received this town from our forbearers, and we feel great pain that we cannot pass it down to our children," he said in a post on his blog.

"We want this Street View imagery to become a permanent record of what happened to Namie-machi in the earthquake, tsunami and nuclear disaster."

Street View was started in 2007, and now provides images from more than 3,000 cities across 48 countries, as well as parts of the Arctic and Antarctica.

Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Source: http://feeds.nbcnews.com/c/35002/f/653387/s/2a14fe05/l/0Lscience0Bnbcnews0N0C0Inews0C20A130C0A30C270C174918350Egoogle0Eadds0Estreet0Eview0Eto0Eghost0Etown0Einside0Ejapan0Enuclear0Ezone0Dlite/story01.htm

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New Gene Markers Reveal Cancer Risk

A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian or prostate cancer, scientists reported Wednesday.

It's the latest mega-collaboration to learn more about the intricate mechanisms that lead to cancer. And while the headway seems significant in many ways, the potential payoff for ordinary people is mostly this: Someday there may be genetic tests that help identify women with the most to gain from mammograms, and men who could benefit most from PSA tests and prostate biopsies.

And perhaps farther in the future these genetic clues might lead to new treatments.

"This adds another piece to the puzzle," said Harpal Kumar, chief executive of Cancer Research U.K., the charity which funded much of the research.

One analysis suggests that among men whose family history gives them roughly a 20 percent lifetime risk for prostate cancer, such genetic markers could identify those whose real risk is 60 percent.

The markers also could make a difference for women with BRCA gene mutations, which puts them at high risk for breast cancer. Researchers may be able to separate those whose lifetime risk exceeds 80 percent from women whose risk is about 20 to 50 percent. One doctor said that might mean some women would choose to monitor for cancer rather than taking the drastic step of having healthy breasts removed.

AP

Vicki Gilbert sits on stone steps in Wiltshire, England in this undated photo made available by the family on Tuesday, March 26, 2013. In 2010, Gilbert was diagnosed with breast cancer and then found she carries the mutated BRCA1 gene which may make her pre-disposed to ovarian cancer. Gilbert decided to have ovaries removed to prevent the potential onset of further cancer, and her breast cancer is in remission. A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person?s risk for breast, ovarian or prostate cancer, scientists reported Wednesday, March 27, 2013. It?s the latest mega-collaboration to learn more about the intricate mechanisms that lead to cancer. (AP Photo) Close

Scientists have found risk markers for the three diseases before, but the new trove doubles the known list, said one author, Douglas Easton of Cambridge University. The discoveries also reveal clues about the biological underpinnings of these cancers, which may pay off someday in better therapies, he said.

Experts not connected with the work said it was encouraging but that more research is needed to see how useful it would be for guiding patient care. One suggested that using a gene test along with PSA testing and other factors might help determine which men have enough risk of a life-threatening prostate cancer that they should get a biopsy. Many prostate cancers found early are slow-growing and won't be fatal, but there is no way to differentiate and many men have surgery they may not need.

Easton said the prospects for a genetic test are greater for prostate and breast cancer than ovarian cancer.

Breast cancer is the most common malignancy among women worldwide, with more than 1 million new cases a year. Prostate cancer is the second most common cancer in men after lung cancer, with about 900,000 new cases every year. Ovarian cancer accounts for about 4 percent of all cancers diagnosed in women, causing about 225,000 cases worldwide.

The new results were released in 13 reports in Nature Genetics, PLOS Genetics and other journals. They come from a collaboration involving more than 130 institutions in the United States, Europe, and elsewhere. The research was mainly paid for by Cancer Research U.K., the European Union and the U.S. National Institutes of Health.

Scientists used scans of DNA from more than 200,000 people to seek the markers, tiny variations in the 3 billion "letters" of the DNA code that are associated with disease risk.

Source: http://abcnews.go.com/Health/wireStory/scientists-find-gene-markers-cancer-risk-18822836

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Darren Elkins nearly missed the call for his UFC on Fox 7 bout because of cell phone charges

For Americans visiting Canada, the cell phone charges can sometimes creep up on you. Your phone will work the same, but weeks later, you get a shocking cell phone bill. UFC featherweight Darren Elkins wasn't going to get hit with that massive phone bill during his trip to Montreal for UFC 158. He ignored phone calls.

Of course, that also meant he nearly missed his chance at filling in at UFC on Fox 7 after Clay Guida pulled out of his bout with Chad Mendes because of an injury.

"Up there (in Canada) I had my phone turned off," Elkins today told MMAjunkie.com Radio "You've got those ridiculous roaming charges and stuff."

His manager ran him down and broke the news of the potential fight. Elkins will face Mendes, the one-time featherweight contender, just a month after fighting Antonio Carvalho and winning with a controversial TKO. Elkins is on a five-fight win streak, so a win over Mendes could push him closer to a title shot.

It's the kind of fight that's definitely worth the roaming charges.

Source: http://sports.yahoo.com/blogs/mma-cagewriter/darren-elkins-nearly-missed-call-ufc-fox-7-215721707--mma.html

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HTC reportedly planning DROID DNA successor

By Simon Evans MEXICO CITY, March 27 (Reuters) - United States central defenders Omar Gonzalez and Matt Besler went into Tuesday's game against Mexico at the Azteca Stadium with just two World Cup qualifying starts between them, but looked like they had been alongside each other for years in a spirited 0-0 draw. Gonzalez, making his third start in a qualifier and Besler making his first, held Mexico at bay in front of more than 95,000 fans as the U.S earned just their second point ever at the home of their arch-rivals. ...

Source: http://news.yahoo.com/htc-reportedly-planning-droid-dna-successor-115028571.html

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Wednesday, March 27, 2013

Lemur lookalikes are two new species, DNA says

Mar. 26, 2013 ? Scientists have identified two new species of mouse lemur, the saucer-eyed, teacup-sized primates native to the African island of Madagascar.

The new study brings the number of recognized mouse lemur species to 20, making them the most diverse group of lemurs known. But because these shy, nocturnal primates look so much alike, it's only possible to tell them apart with genetic sequencing.

The new mouse lemurs weigh 2.5 to 3 ounces (about 65 to 85 grams) and have grey-brown fur. "You can't really tell them apart just looking at them through binoculars in the rainforest," said senior author Peter Kappeler of the German Primate Center in Goettingen, who earned his PhD at Duke in 1992.

The researchers named one of the new species the Anosy mouse lemur, or Microcebus tanosi. Anosy mouse lemurs are close neighbors with grey mouse lemurs and grey-brown mouse lemurs, but the genetic data indicate they don't interbreed.

The researchers named the other new species the Marohita mouse lemur, or Microcebus marohita, after the forest where it was found. In Malagasy, the word "marohita" means "many views."

"Despite its species' name, this mouse lemur is threatened by ongoing habitat destruction, and 'many views' of its members are unlikely," the researchers write.

The two new species were first captured by co-author Rodin Rasoloarison of the University of Antananarivo in Madagascar during trips to the eastern part of the country in 2003 and 2007. Rasoloarison weighed and measured them and took tiny skin samples for genetic analysis in the lab.

Co-authors Anne Yoder and Dave Weisrock, both at Duke University at the time, analyzed two mitochondrial and four nuclear DNA genes to figure out where the animals fit into the lemur family tree. Their genetic analyses were published in 2010, but this is the first time the species have been formally named and described.

Funded by a grant from the German Research Foundation, the study is published in the March 26 online issue of the International Journal of Primatology.

During a 2012 return trip to the forest where the Marohita mouse lemur lives, Rasoloarison discovered that much of the lemur's forest home had been cleared since his first visit in 2003. The state of the lemur's habitat prompted the International Union for the Conservation of Nature (IUCN) to classify the new species as "endangered" even before it was formally described.

"This species is a prime example of the current state of many other lemur species," Kappeler said. Mouse lemurs have lived in Madagascar for 7 to 10 million years. But since humans arrived on the island some 2,500 years ago, logging and slash and burn agriculture have taken their toll on the forests where these tree-dwelling primates live.

Only 10 percent of Madagascar's original forests remain today, which makes lemurs the most endangered mammals in the world according to the IUCN.

"Knowing exactly how many species we have is essential for determining which areas to target for conservation," Kappeler said.

A better understanding of mouse lemur diversity could help humans too. Mouse lemurs are a closer genetic match to humans than mice and rats, the most common lab animals. At least one species -- the grey mouse lemur (Microcebus murinus) -- develops a neurological disease that is strikingly similar to human Alzheimer's, so the animals are considered important models for understanding the aging brain.

"But before we can say whether a particular genetic variant in mouse lemurs is associated with Alzheimer's, we need to know whether that variant is specific to all mouse lemurs or just select species," said Lemur Center Director Anne Yoder.

"Every new mouse lemur species that we sample in the wild will help researchers put the genetic diversity we see in grey mouse lemurs in a broader context," she said.

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Story Source:

The above story is reprinted from materials provided by Duke University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Rodin M. Rasoloarison, David W. Weisrock, Anne D. Yoder, Daniel Rakotondravony, Peter M. Kappeler. Two New Species of Mouse Lemurs (Cheirogaleidae: Microcebus) from Eastern Madagascar. International Journal of Primatology, 2013; DOI: 10.1007/s10764-013-9672-1

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/_xJqX-S3ItA/130326101523.htm

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